The Stopwatch Complex forms during an extended mitosis
During an extended mitosis PLK1 triggers the formation of a Mitotic Stopwatch Complex that stabilizes and activates the tumor suppressor p53. This complex accumulates during one or successive prolonged mitoses and ultimately causes cell arrest or cell death.
Date:
25 March 2024
Credit:
Meitinger et al., 2024
Copyright OIST (Okinawa Institute of Science and Technology Graduate University, 沖縄科学技術大学院大学). Creative Commons Attribution 4.0 International License (CC BY 4.0).
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