Monolith

It can provide information about binding affinity.

CF-IAS_A015_Monolith

・Quantify molecular interactions between a target and ligand by detecting changes in fluorescence intensity while a temperature gradient is applied over time.

・Competition Assays: Assess relative affinities of two or more molecules for the same target.

・Ternary binding events: Characterize interactions that involve three or more binding partners.

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Features

・Optics: Pico Red

・Sample number: max 24

・Dynamic range: 1 pM to mM

・Detected molecular range: 101 – 107 Daltons

・Minimum sample volume: 4 ul

・Temperature control: 20-40℃ ±0.5℃

・Fluorescence channels: 1 (pico RED) or 2 (pico RED & LabelFree (UV) or pico RED & Blue