Sequencing Specialist

The position

This position is dedicated to systematically capturing and recording the "hard-to-document knowledge (tacit knowledge)" inherent in sequencing experiments, through hands-on experimental work.

At the Sequencing Section (SQC) of the Okinawa Institute of Science and Technology (OIST), the position involves introducing and improving protocols for sample preparation, library construction, sequencer operation, and related procedures—building on the fundamentals of molecular biology experiments—in collaboration with members of the section and the broader project. The role also includes establishing a framework for documenting the processes of trial and error and decision-making in the form of text, video, audio, and dialogue (Q&A), and engaging with external experts to acquire, organize, and edit metadata through filming and interviews. These records will serve as primary source material both for educational content on life science experiments and as training data for experimental-support AI tools. We provide an environment in which advanced sequencing techniques, the development of new protocols, and tasks such as filming and editing can be acquired progressively through on-the-job experience.

This work contributes to the research and development project "BioSkillDX: Tacit Knowledge Acquisition and Work Support for Life Science Experimental Tasks" (Principal Investigator: Professor Yoichi Sato, The University of Tokyo; Project Period: August 1, 2025 – July 31, 2030), conducted under the Economic Security Technology Area (K Program) of the Japan Science and Technology Agency (JST). At the intersection of life sciences and AI, this position offers a rare opportunity to transform experimental expertise into socially valuable data and educational materials.

About OIST

The Okinawa Institute of Science and Technology Graduate University was established in 2011 to contribute to the development of science and technology worldwide and to serve as a hub of innovation in Okinawa. OIST is a dynamic new graduate university of science and technology in Okinawa Prefecture, Japan which offers a 5-year PhD program and brings together outstanding researchers from across the country and across disciplines to conduct cutting-edge scientific research.

The university is located on 85 hectares of protected forestland overlooking a beautiful shoreline and coral reefs. The campus is striking architecturally, and the facilities are outstanding. To facilitate multidisciplinary research, there are no academic departments. Outstanding resources and equipment are provided and managed to encourage easy access and collaboration.

English is the official language of the University, and the university research community is fully international, with more than 50 countries represented. OIST is rapidly gaining recognition in the worldwide academic community as a model for excellence in education and research, and our unwavering commitment to scientific and technological innovation is dedicated to generating progress that will fuel Okinawa's economic growth.

Responsibilities

This position encompasses the responsibilities described below, building on hands-on experience with the fundamentals of molecular biology experiments (such as DNA/RNA extraction, PCR, cloning, ligation, and enzymatic reactions including reverse transcription) and an understanding of their underlying principles. Prior experience in advanced sequencing techniques or in the development of new protocols is not required at the time of hiring; we provide an environment in which these skills can be progressively acquired through on-the-job experience, in collaboration with members of the section and the broader project.

Execution of Sequencing Experiments and Development of New Protocols:
Carry out experiments that are difficult to perform reliably with existing methods, starting with DNA extraction as the foundation of sequencing. Concrete examples include constructing and validating sample-preparation protocols that directly determine the quality of sequencing data, such as genomic DNA extraction from unknown species and the technically demanding "Ultra-long DNA extraction." Optimization of techniques and condition settings is conducted through iterative trial and error, in collaboration with members of the section and the broader project.

Documentation of Experiments and Construction/Operation of the Recording Environment:
Document the process of developing new protocols (including the evolution of methods and key decision points) in the form of text, video, audio, and dialogue (Q&A). Construct and operate a standardized recording environment shared across the project. The accumulated records will be used both as educational content for life science experiments and as training data for the development of experimental-support AI tools.

Collaboration with External Experts and Support for Metadata Acquisition:
To expand the AI training-data corpus, support the work of acquiring and organizing metadata that captures the techniques and tacit knowledge of experts from outside OIST. Specific tasks include planning panel discussions with these experts and providing on-site interviewing and experimental assistance. Additional duties include collecting video, audio, and dialogue data through filming and interviews, as well as organizing and editing the collected data (such as adding subtitles and annotations, and linking related metadata). Scheduling and on-site coordination during visits are also part of the role. Prior experience in filming, editing, or related tasks is not required at the time of hiring; we provide an environment for learning alongside members of the section and the broader project as the work proceeds.

Qualifications

(Required)

  1. Master's degree or higher in a science or technology field, or equivalent professional experience.
  2. Hands-on experience with the fundamentals of molecular biology experiments (such as DNA/RNA extraction, PCR, cloning, ligation, and enzymatic reactions including reverse transcription), along with an understanding of their underlying principles.
  3. Ability to conduct experiments independently and proactively.
  4. Logical thinking skills, with the ability to work systematically and accurately.
  5. Ability to communicate effectively in Japanese.
  6. Fairness, integrity, and a strong commitment to teamwork.
  7. Willingness to continuously work toward improving the quality, reproducibility, and efficiency of experiments.
  8. Comfort with the routine use of experimental equipment, electronic devices, PCs, and AI tools when necessary.
  9. Willingness to engage—even without prior experience—in metadata acquisition and organization tasks (including filming, interviewing, and editing).


(Preferred)
Note: The following items are not required for application. Candidates who meet only the required qualifications are also welcome to apply.

  1. Interest in noticing minor anomalies or bottlenecks in experimental methods and using them as a starting point to refine and improve techniques.
  2. Willingness to actively engage in the launch and setup of new experimental technologies and equipment.
  3. Experience in filming, video editing, audio editing, data organization, or related tasks.
  4. Experience in sequencing-related experiments (such as library construction and QC).
  5. Experience in highly demanding sample preparation (such as Ultra-long DNA extraction).
Compensation and Benefits

In accordance with the OIST Employee Compensation Regulations(RS1-RS3).

Benefits:

Application Documents

Cover letter in Japanese (English version preferred)

Curriculum vitae in Japanese (English version preferred)

*  Please submit your Japanese CV (履歴書) and work history (職務経歴書) in one combined file.
*    Up to 2 references may be requested during the final interview stage.
*    Please click APPLY HERE to be redirected to our application platform (Interfolio) and follow the instructions there to upload the required documents.

Declaration

Declaration

  • OIST Graduate University is an equal opportunity, affirmative action educator and employer and is committed to increasing the diversity of its faculty, students and staff.
  • Information provided by applicants or references will be kept confidential in accordance to the OIST Privacy Policy; documents will not be returned.
  • Recruiting Organization: Okinawa Institute of Science and Technology School Corporation 
  • Prevention of Passive Smoking: No smoking indoors
  • Please view our policy for rules on external professional activities: Rules for Concurrent Appointment.
  • Further details about the University can be viewed on our website.
Job Type
Research support
Starting Date
As early as possible
Employment Term

Full-time, 2-year fixed-term contract including a 6-month probationary period, renewable up to the end of the project period (July 31, 2030)

Working Hours

9:00-17:30 (Discretionary)

 

Holidays
Saturday, Sunday, National holidays, and Year-end and New Year holidays (Dec. 29 – Jan. 3)

 

Leave
Annual Paid Holidays, Summer Leave, Sick Leave, and Special Leave

Report to
Sequencing Section Leader
Job Location
Main Campus: 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa
Application Deadline
Applications will be accepted until all positions are filled.
*Application will be closed once the position is filled.

Thank you for your interest in this opportunity. Please note that only shortlisted candidates will be contacted.

If you have any questions, please contact us at