30 Jul 2019
Scientific discoveries are exciting, but scientists must also develop new approaches to make such discoveries possible. Researchers at the Okinawa Institute of Science and Technology Graduate...
Type: News Article
25 Jul 2019
Professor Bernd Kuhn and Dr. Christopher Roome, who wrote a primer and book chapter on their voltage imaging approach.
Type: Photo
25 Jul 2019
Looking down a microscope, researchers place a probe beside the cell membrane of a Purkinje neuron and inject fluorescent dye. Once correctly in place, the dye molecules provide insight on the brain...
Type: Photo
25 Jul 2019
This single Purkinje neuron has been stained using Kuhn’s voltage imaging approach, allowing scientists to visualize its activity.
Type: Photo
28 Aug 2018
Our brain cells control every aspect of our lives – from the movements we make to the memories we form. But capturing the activity of neurons in the form of electric impulses isn’t easy. Information...
Type: News Article
28 Aug 2018
Dr. Christopher Roome (left) and Prof. Bernd Kuhn (right) from the Optical Neuroimaging Unit at OIST.
Type: Photo
28 Aug 2018
Spatially and temporally resolved map of a Purkinje neuron dendrite. Every red hotspot indicates an input to the dendrite. The red lines indicate activation of the full dendritic tree.
Type: Photo
28 Aug 2018
A single Purkinje neuron was filled with ANNINE dye through a pipette at the cell body (top). A typical neuron has a cell body with many tree-shaped processes called dendrites, and a long cable-like...
Type: Photo
8 Dec 2017
OIST professors Izumi Fukunaga and Bernd Kuhn are among the scientists who have supported the Science Bridge project.
Type: Photo
Twelve speakers are placed around the mouse. The speakers generate sound based on the movement of the mouse running on the spherical treadmill (left). When the mouse reaches the virtual sound source it will get a droplet of sugar water as a reward.
20 Sep 2016
The research team of Dr. Akihiro Funamizu, Prof. Bernd Kuhn, and Prof. Kenji Doya from OIST built a virtual reality system in which a mouse can be made to believe it was walking around freely,...
Type: Photo
Probabilistic neural decoding allows for the estimation of the goal distance from neuronal activity imaged from the parietal cortex. Neurons could predict the goal distance even during sound omissions. The prediction became more accurate when sound was given. These results suggest that the parietal cortex predicts the goal distance from movement and updates the prediction with sensory inputs, in the same way as dynamic Bayesian inference.
20 Sep 2016
Probabilistic neural decoding allows for the estimation of the goal distance from neuronal activity imaged from the parietal cortex. Neurons could predict the goal distance even during sound...
Type: Photo
A depiction of the location of the parietal cortex in a mouse brain can be seen on the left. On the right, neurons in the parietal cortex are imaged using two-photon microscopy.
20 Sep 2016
Dr. Akihiro Funamizu, Prof. Bernd Kuhn, and Prof. Kenji Doya analyzed brain activity in the parietal cortex of mice as they approached a target under interrupted sensory inputs....
Type: Photo
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