17 Sep 2021 - 14:16
Highlights Researchers in Japan looked at saliva samples taken from two different age groups to see if the composition of saliva changes as one ages. Despite the difficulties with working with...
Type: Press release
10 Sep 2021 - 17:17
A heat-map, where red shows high levels of a compound, and blue shows low levels of a compounds, reveals the link between certain metabolites and dementia. Compounds in sub-group A were typically...
Type: Photo
10 Sep 2021 - 17:12
Highlights Researchers have identified 33 metabolic compounds that are linked to dementia Seven metabolites were found at higher levels in patients with dementia, compared to healthy elderly...
Type: Press release
7 Apr 2020 - 09:11
Globally, human society is aging. A side-effect of this is that age-related disorders, such as frailty, are becoming increasingly common. Frailty includes, not only physical disabilities, but also a...
Type: Press release
5 Feb 2019 - 13:35
Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don’t get stuck. But in...
Type: News Article
31 Jan 2019 - 13:41
(Left to right) Prof. Mitsuhiro Yanagida, technician Orie Arakawa, and Dr. Norihiko Nakazawa of the G0 Cell Unit authored a paper on the enzyme DNA topoisomerase II (topo II) a critical target...
Type: Photo
31 Jan 2019 - 13:29
With DNA topoisomerase II (topo II) intact, DNA in fission yeast cells replicates normally and is split evenly between two daughter cells (left). When under the effects of anti-cancer drug ICRF-193,...
Type: Photo
31 Jan 2019 - 13:28
Casein kinase II (CKII) phosphorylates DNA topoisomerase II (topo II), thus activating the ATPase domain of the enzyme (left). This activation cancels the effects of anti-cancer drug ICRF-193. If...
Type: Photo
31 Jan 2019 - 13:27
DNA topoisomerase II (topo II), a master regulator of DNA metabolism for cell proliferation, is a critical target for anti-cancer therapy.
Type: Photo
31 Jan 2019 - 09:31
Fasting may help people lose weight, but new research suggests going without food may also boost human metabolic activity, generate antioxidants, and help reverse some effects of aging. Scientists at...
Type: Press release
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