Tracking procedure of individual cell growth. Left: Individual lens epithelial cells are observed using a confocal microscope. Middle: Each cell is assigned a spot of a specific color, depending on the cell’s classification: dividing, non-dividing, or dead/dying. Right: The movement patterns of each cell are tracked and marked by a trajectory line. The color of the line indicates the speed at a particular location.
13 Feb 2017
Tracking procedure of individual cell growth. Left: Individual lens epithelial cells are observed using a confocal microscope. Middle: Each cell is assigned a spot of a specific color, depending on...
Type: Photo
Zebrafish lens epithelial cells were bioengineered to express fluorescent proteins mCherry-zGem and GFP-tagged histones. Early in the cell cycle, only GFP-histones are expressed, resulting in a green color. As the cell progresses through the cell cycle, mCherry-zGem is expressed at progressively higher levels, shifting the cell’s apparent color along the color spectrum ending in a deep red color.
13 Feb 2017
Zebrafish lens epithelial cells were bioengineered to express fluorescent proteins mCherry-zGem and GFP-tagged histones. Early in the cell cycle, only GFP-histones are expressed, resulting in a green...
Type: Photo
Diagram of the zebrafish eye. Left: photograph of the zebrafish eye under a microscope, with the anterior region situated at the top of the photograph and the posterior region at the bottom. Right: diagram of the zebrafish eye lens depicting where the lens epithelial and fiber cells are relative to the rest of the eye.
13 Feb 2017
Diagram of the zebrafish eye. Left: photograph of the zebrafish eye under a microscope, with the anterior region situated at the top of the photograph and the posterior region at the bottom. Right:...
Type: Photo
Live zebrafish embryos were immobilized under a confocal microscope so that their eye development could be tracked in real time. The lens of the eye contained bioengineered cells that would express proteins that produced a color visible under the microscope.
13 Feb 2017
Live zebrafish embryos were immobilized under a confocal microscope so that their eye development could be tracked in real time. The lens of the eye contained bioengineered cells that would express...
Type: Photo
28 Mar 2016
Prof Greg Stephens, adjunct professor at the Okinawa Institute of Science and Technology Graduate University (OIST), and...
Type: News Article
16 Oct 2014
The proliferation of cells, in particular the orientation in which they divide, is key in regulating the shapes of tissues. However, the cellular mechanisms that govern cell proliferation and cell...
Type: News Article
16 Oct 2014
The diagram above shows a cross section of the zebrafish lens. Lens epithelium covers the anterior half of lens fiber core and ends at the peripheral zone which is roughly at the equator of the lens...
Type: Photo
16 Oct 2014
The first and second authors, Dr. Toshiaki Mochizuki (left) and Dr. Shohei Suzuki (right) standing next to a PC displaying the fluorescent image, which was used to study the zebrafish lens epithelium...
Type: Photo
19 Aug 2014
Before cells divide, they create so much genetic material that it must be wound onto spools before the two new cells can split apart. These spools are actually proteins called histones, and they must...
Type: News Article
Histones Spooling DNA
19 Aug 2014
DNA is wound onto spools to make it more compact, so that it will fit inside chromosomes. Image courtesy of the...
Type: Photo
Zebrafish Retina Development
19 Aug 2014
This figure shows the differences between a wild type zebrafish, labeled wt, and the SLBP mutant used in this experiment, labeled rw440. Moving from left to right, the images show the embryo at 3, 4...
Type: Photo
Professor Ichiro Masai in the Zebrafish Lab
19 Aug 2014
Dr. Ichiro Masai points to one strain of mutant zebrafish in his lab at OIST.
Type: Photo
Subscribe to Developmental Neurobiology Unit (Ichiro Masai)