8 Aug 2022 - 15:34
Group photo of the Cellular and Molecular Synaptic Function Unit, that Prof. Tomoyuki Takahashi (fifth from left) leads. This image appeared in the news article “Long-standing professor named 2022...
Type: Photo
8 Aug 2022 - 10:00
Physiology is the study of processes and mechanisms that make up living organisms – from chemical and molecular interactions to entire body systems. At the Okinawa Institute of Science and...
Type: News Article
22 Jun 2022 - 11:17
Highlights A new study has revealed how tau – a microtubule-binding protein that is implicated in Alzheimer’s disease – weakens transmission across synapses in the brains of mice When injected...
Type: Press release
22 Dec 2020 - 00:00
Neurons are like the electrical wiring of our brains, responsible for receiving information from the outside world and conveying this information to the rest of our body. To work correctly, they need...
Type: Press release
24 Apr 2020 - 15:43
Hailed as one of the most important medical advances, the discovery of general anesthetics – compounds which induce unconsciousness, prevent control of movement and block pain – helped transform...
Type: News Article
24 Apr 2020 - 15:02
When vesicles fuse with the presynaptic membrane during exocytosis, the synaptic vesicle membrane is incorporated into the terminal membrane, increasing its surface area. During endocytosis, vesicles...
Type: Photo
24 Apr 2020 - 14:56
The experiment used genetically modified mice that had a light sensitive protein (green circle), usually found in the eye, embedded in the membrane of the presynaptic neurons in one area of the brain...
Type: Photo
24 Apr 2020 - 14:54
The large size of the calyx of Held allows scientists to visualize and manipulate the synapse. The electrodes touching the neurons can be used to evoke and record electrical signals. The frequency of...
Type: Photo
24 Apr 2020 - 14:49
(1) A nerve impulse arrives. (2) This causes calcium ion channels to open, resulting in an influx of calcium ions in the terminal. (3) This causes synaptic vesicles to fuse with the terminal membrane...
Type: Photo
25 Dec 2019 - 10:38
Researchers in the Cellular and Molecular Synaptic Function Unit at the Okinawa Institute of Science and Technology Graduate University (...
Type: News Article
25 Dec 2019 - 10:26
Fig 5: The authors of the new study, published in Journal of Neuroscience. From left to right: Dr Lashmi Pyriya, Dr. Kohgaku Eguchi, Dr Laurent Guillaud, Professor Tomoyuki Takahashi, Dr. Han-Ying...
Type: Photo
25 Dec 2019 - 10:23
Fig 4 Left, Experimental protocol of simultaneous recording of APs from presynaptic (right crescent) and postsynaptic (left round) structures. Middle, Postsynaptic APs evoked by presynaptic APs (not...
Type: Photo
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