28 Aug 2020
A protein that’s common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit...
Type: Press release
28 Aug 2020
Mice lacking CNOT3 in pancreatic beta cells have fewer insulin-producing cells, leading to diabetes.
Type: Photo
28 Aug 2020
The researchers from the Cell Signal Unit at OIST. From left, Dr. Akiko Yanagiya, Dr. Dina Mostafa, and Professor Tadashi Yamamoto.
Type: Photo
18 Dec 2015
Ever imagined you could eat all the mouthwatering, festive food during winter holidays and never worry about an expanding waistline? For many people throughout the world, being overweight or worse...
Type: Press release
18 Dec 2015
The animation illustrates OIST research’s findings in obesity: the degradation of Ucp1 mRNA in fat cells is mediated by Tob and Cnot7.  
Type: Video
4 Dec 2015
Recent research has shown that the cells in our bodies teeter on the brink of death. They possess intricate molecular mechanisms that promote either suicide or survival. The concept is known as...
Type: News Article
Cell Undergoing Necroptosis
4 Dec 2015
CNOT3-depleted mouse cell undergoes necroptosis. The cell membrane swells and later breaks, leaking its contents into the intercellular space.
Type: Photo
Suppression of the mRNA turn-over leads to necroptosis
4 Dec 2015
Intact CCR4-NOT complex (on the left) suppresses the messenger RNAs (mRNAs) encoding RIPK1 and RIPK3 proteins, thereby aiding cell survival. CNOT3-depleted cells, in which the CCR4-NOT complex does...
Type: Photo
Dr Toru Suzuki
4 Dec 2015
Dr Suzuki, group leader at the Cell Signal Unit at OIST
Type: Photo
25 Sep 2014
OIST Prof. Tadashi Yamamoto is receiving the Tomizo Yoshida Award from The Japanese Cancer Association (JCA) for “outstanding achievement in the...
Type: News Article
24 Sep 2014
(Above) Normal fibroblasts (Below) Fibroblasts transformed by ERBB2
Type: Photo
24 Sep 2014
Professor Tadashi Yamamoto
Type: Photo
Subscribe to Cell Signal Unit (Tadashi Yamamoto)