New appearance seen in fission yeast following ICRF-193 treatment

21 Oct 2016

The top figure depicts the normal appearance of fission yeast following replication and subsequent separation. Chromosomes are seen in pink and the mitotic spindle is in green. The bottom figure shows the ICRF-193 treated cells, which are unable to separate normally. The chromosomes can partially separate, as seen in the far left, but as the spindle elongates, it is unable to further separate the chromosomes, eventually bending and snapping, as seen in the far right of the figure. 

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