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Figure 5-2. Prediction of a test compound (PubChem CID: 3795) against 180 FluMap proteins using systemsDock. FluMap describes the intermolecular network of influenza A virus life cycle from (1) entry, (2) endocytosis, (3) fusion, (4) transcription/translation, (5) assembly, (6) packaging to (7) budding. Docking scores are converted into white/red color according to a cutoff value at 5.52 pKd (white: inactive; red: active; gray: not in the test or no results). Results are projected on the pathway map. The JAK1 protein, which plays a major role in the JAK/STAT signaling pathway, is enclosed in a black frame.
Copyright OIST (Okinawa Institute of Science and Technology Graduate University, 沖縄科学技術大学院大学). Creative Commons Attribution 4.0 International License (CC BY 4.0).