Immune Signal Unit Explains Key Immune System Regulator

Researchers describe how the transcription factor JunB, which modulates gene expression, plays a critical role in keeping the immune system in line in mice.

Researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) have now described how a specific transcription factor, which modulates gene expression, plays a critical role in keeping the immune system in line in mice. The key transcription factor, known as JunB, helps control the activity of cells whose job it is to suppress immune activity. The results, published on December 17, 2018, in Nature Communications, could give important insight into the development of autoimmune disease and cancer immunosuppression.

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18 December 2018

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In the Media

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