Imaging neurons in a living mouse

Neurons in the brain are labelled with fluorescent sensors that vary in fluorescence intensity based on changes in voltage or calcium level within the neurons. Here, the neurons are imaged using a two-photon microscope and then reconstructed in 3-D. Two-photon microscopy also allows scientists to detect changes in fluorescence, and therefore measure the activity of these neurons in real-time.

Neurons in the brain are labelled with fluorescent sensors that vary in fluorescence intensity based on changes in voltage or calcium level within the neurons. Here, the neurons are imaged using a two-photon microscope and then reconstructed in 3-D. Two-photon microscopy also allows scientists to detect changes in fluorescence, and therefore measure the activity of these neurons in real-time.

Date:

12 April 2021

Creator:

danielle-ellenby

Copyright OIST (Okinawa Institute of Science and Technology Graduate University, 沖縄科学技術大学院大学). Creative Commons Attribution 4.0 International License (CC BY 4.0).

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Research

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