The vesicle cycle and relevant interactions

Left, a labelled diagram of the vesicle cycle. The clustered reserve pool in the top left is shown as pink circles, with one circle moving to join the recycling pool, blue.  On the right, two vesicles above a membrane, with model surface interactions labeled, including neurotransmitter packing, vesicle-vesicle protein interactions, vesicle-cytosolic protein interactions, vesicle-membrane protein interactions, vesicle protein lateral diffusion, inter-vesicle protein-protein interactions.

Left: The different pools involved in the vesicle cycle. Vesicles dock to form a readily releasable pool. At the membrane surface, vesicles can be rapidly endocytosed by dynamin to form in addition a readily retrievable pool. Right: The wide variety of interactions accounted for within the researcher’s model.

Date:
29 May 2025
Credit:
Gallimore et al., 2025.
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