onu FY2013 Annual Report 6

onu FY2013 Annual Report 6

Figure 4: The spike/plateau potentials are mediated by NMDA receptors as can be shown by pharmacology (CPP application) and two-photon imaging. A TC neuron (A) is stimulated by glutamate application to the dendrite (location indicated by asterix). Simultaneous electrical (B) and optical recording (two-photon calcium recordings, C) show dendritic spike/plateau potentials which are almost completely blocked by CPP, a NMDA receptor antagonist. Also strong glutamate application is not able to recover the potential (D).

Date:
06 March 2024
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