nru FY2020 Annual Report 5

nru FY2020 Annual Report 5

Figure 4: Preliminary studies using dLight1.3b under control (ACSF), methylphenidate 30 mM (MPD) and MPD plus 1 mM Raclopride (MPD+RAC) conditions. Each F/F0 image is the average of all frames acquired during 1 second (Baseline, 10 frames) before electrical field stimulation using a bipolar electrode, visible in images. Stim 1-2 s, last second of stimulation. 1-2s Post-Stim, response 1s after end of stimulation. Rainbow scale ranges between lowest (dark blue) and highest (red) fluorescence values. Stimulation 20 pulses, 2ms/phase, at 10Hz. Scale bar 200 µm. Paper in preparation, Julie Chouinard.

Date:
11 March 2024
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