Prof. Kono Helps Uncover How Cells Split Smoothly
Prof. Keiko Kono of the Membranology Unit co-authored a new study unpacking the intricacies of mitosis. She and her colleagues discovered that cyclin-dependent kinase 1, or Cdk1, maintains just enough tension at the cell membrane to allow the cell to divide perfectly, every time. Without proper modulation by Cdk1, the membrane becomes too taut and cell division cannot progress beyond a certain checkpoint.
The research, published February 28, 2019 in Nature Communications, reports the first case in which excess tension at the cell membrane disrupts cell division, rather than too little tension.
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