Immune Signal Unit Explains Key Immune System Regulator
18 Dec 2018
Researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) have now described how a specific transcription factor, which modulates gene expression, plays a critical role in keeping the immune system in line in mice. The key transcription factor, known as JunB, helps control the activity of cells whose job it is to suppress immune activity. The results, published on December 17, 2018, inNature Communications, could give important insight into the development of autoimmune disease and cancer immunosuppression.