Cellular and Molecular Synaptic Function Unit (Tomoyuki Takahashi)
26 Mar 2018 - 14:48
The chemical structure of “caged” GABA (left) and free GABA (right). After UV illumination, GABA is released from the compound.
26 Mar 2018 - 14:43
The researchers made paired whole-cell recordings using glass capillary pipettes. Caged GABA was injected using presynaptic pipettes.
26 Mar 2018 - 14:41
Prof. Takahashi sits in his office at OIST, which overlooks tropical jungle scenery.
26 Mar 2018 - 14:35
The process of recycling at a synapse. First, lipid membrane capsules are recovered from the pre-synaptic terminal membrane. Then, the vesicles are refilled with neurotransmitter.
26 Mar 2018 - 14:33
At the synapse, an electrical signal arrives at the pre-synaptic terminal and triggers vesicles to release neurotransmitters into the synaptic cleft. The neurotransmitters activate receptors in the...
26 Mar 2018 - 14:24
Neurons in the brain form tangled webs of connections. Within these webs, cells communicate with each other to control motor, cognitive and other functions. A neuron, when activated,...
Type: News Article
14 Jun 2017 - 09:53
While the mechanism of transmission of information at the contact point between two neurons – the famous synapse – has been thoroughly studied, the transportation of this information within the...
Type: News Article
14 Jun 2017 - 09:42
3D localization and distribution of synaptic vesicles labeled with quantum dots in giant pre-synaptic terminal expressing green fluorescent protein (GFP). Vesicles are color-coded according to their...
14 Jun 2017 - 09:40
14 Jun 2017 - 09:37
14 Jun 2017 - 09:34
3 Jun 2017 - 06:30
Parkinson’s disease is a debilitating neurological illness that affects approximately 10 million people worldwide. It is marked by a progressive decline in physical function, the most iconic being...
Type: Press release