Paired-end shotgun sequencing
Paired-end shotgun sequencing works by first creating multiple copies of the human genome. Then, each copy of the genome is “shotgunned” into smaller fragments, with the breakages occurring at random points in the genome. The ends of the fragments are sequenced and a computer algorithm matches overlapping ends together to piece the genome back together.
Paired-end shotgun sequencing works by first creating multiple copies of the human genome. Then, each copy of the genome is “shotgunned” into smaller fragments, with the breakages occurring at random points in the genome. The ends of the fragments are sequenced and a computer algorithm matches overlapping ends together to piece the genome back together.
Copyright OIST (Okinawa Institute of Science and Technology Graduate University, 沖縄科学技術大学院大学). Creative Commons Attribution 4.0 International License (CC BY 4.0).
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