A depiction of the location of the parietal cortex in a mouse brain can be seen on the left. On the right, neurons in the parietal cortex are imaged using two-photon microscopy.
20 Sep 2016
Dr. Akihiro Funamizu, Prof. Bernd Kuhn, and Prof. Kenji Doya analyzed brain activity in the parietal cortex of mice as they approached a target under interrupted sensory inputs....
Type: Photo
Mice are eager to find the virtual sound source to get the sugar water reward. When the mice get closer to the goal, they increase licking in expectation of the sugar water reward. They increased licking when the sound is on but also when the sound is omitted. This result suggests that mice estimate the goal distance by taking their own movement into account.
20 Sep 2016
In a collaboration of the Neural Computation Unit and the Optical Neuroimaging Unit at the Okinawa Institute of Science and Technology Graduate University (OIST), Dr. Akihiro Funamizu, Prof. Bernd...
Type: Photo
Probabilistic neural decoding allows for the estimation of the goal distance from neuronal activity imaged from the parietal cortex. Neurons could predict the goal distance even during sound omissions. The prediction became more accurate when sound was given. These results suggest that the parietal cortex predicts the goal distance from movement and updates the prediction with sensory inputs, in the same way as dynamic Bayesian inference.
20 Sep 2016
Probabilistic neural decoding allows for the estimation of the goal distance from neuronal activity imaged from the parietal cortex. Neurons could predict the goal distance even during sound...
Type: Photo
20 Sep 2016
Suppose you woke up in your bedroom with the lights off and wanted to get out. While heading toward the door with your arms out, you would predict the distance to the door based on your memory of...
Type: Press release
Twelve speakers are placed around the mouse. The speakers generate sound based on the movement of the mouse running on the spherical treadmill (left). When the mouse reaches the virtual sound source it will get a droplet of sugar water as a reward.
20 Sep 2016
The research team of Dr. Akihiro Funamizu, Prof. Bernd Kuhn, and Prof. Kenji Doya from OIST built a virtual reality system in which a mouse can be made to believe it was walking around freely,...
Type: Photo
16 Sep 2016
Prof. Bernd Kuhn, Dr. Akihiro Funamizu and Prof. Kenji Doya post in front of lab equipment.
Type: Photo
1 Sep 2014
The brain is a complicated network of small units called neurons, all working to carry information from the outside world, create an internal model, and generate a response. Neurons sense a signal...
Type: News Article
Stimulating a Depolarized TC Neuron
1 Sep 2014
This figure shows how glutamate stimulation lifts the TC Neuron’s membrane potential so that more action potentials are generated. The graph at left shows action potentials when Dr. Augustinaite...
Type: Photo
Stimulating a TC Neuron
1 Sep 2014
This figure shows how the NMDA spike/plateau grows with stronger glutamate stimulation. Colors indicate the strength of the stimulation, yellow being the strongest and most glutamate.
Type: Photo
Dr. Bernd Kuhn & Dr. Sigita Augustinaite
1 Sep 2014
Dr. Bernd Kuhn, left, and Dr. Sigita Augustinaite, right, stand in Dr. Kuhn’s office in the Optical Neuroimaging Unit at OIST.
Type: Photo
TC Neuron
1 Sep 2014
A thalamocortical, or TC neuron labeled with fluorescent dye, as used in Dr. Augustinaite’s study. The image shows a voltage recording device, at bottom left, entering the yellow cell body, and a...
Type: Photo
12 Apr 2013
The old saying is “if it’s not broken, don’t fix it,” but sometimes, especially in science, it’s worth reviewing old methodologies to see they’re keeping up with the rapidly advancing technological...
Type: News Article
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